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KMID : 0043319820050020093
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Archives of Pharmacal Research
1982 Volume.5 No. 2 p.93 ~ p.96
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A Novel Bromolactonization Reaction Using Racemic 3-Bromo-5-isobutyl-5-methylhydantoin
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Cho YS
Jew SS/Chung YS
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Abstract
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By using racemic 3-bromo-5-isobutyl-5-methylhydantoin (3a’’) in dry N, N-dimethylformamide which is a model reagent for asymmetric bromolactonization, bromolactonization of a series of olefinic acids was carried out to furnish corresponding bromolactones in moderate yields.
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